Mycosis fungoides (MF) is derived cutaneous T-cell lymphoma, which is often characterized by mild lesions, although it may be become a malignant transformation in the direction of growth of helper T-cell. The disease affects all races, it can occur at any age, more common in males. The diagnosis is often determined by the morphology of the lesions that are initially stains, over time it may take the form of infiltrative or nodular. Investigations carried out in the early stages of the disease, including histopathological examination, we do not always confirm the diagnosis of MF. We present a case of MF patients in whom we encountered diagnostic and therapeutic problems. Special attention is interdisciplinary in relation to this group of patients. Good cooperation between various specialists can contribute to faster diagnosis and better treatment of these patients.

Key words: granuloma fungoides, primary cutaneous T-cell lymphoma CTCL, mycosis fungoides.